Supplementary Figure 9: GCs exhibit similar activity under two anesthesia regimes.
From: Broadly tuned and respiration-independent inhibition in the olfactory bulb of awake mice
(a) Histogram of mean spontaneous firing rates from ketamine-xylazine (grey) and isoflurane (black) animals. Mean ± s.e.m. results are summarized in boxplots (kx = 2.13 ± 0.92, iso = 2.42 ± 0.71 ). Rates between these two groups did not significantly differ (U(21) = 54, p = 0.65). Kx = ketamine-xylazine, Iso = isoflurane. (b) Ranked tuning curves for both during odor presentation and after odor offset are plotted. Data are represented as the mean ± s.e.m. for each odor and plotted in order from the odor eliciting the most inhibitory response to the odor eliciting the most excitatory response. Curve slope was calculated for both the kx and isoflurane conditions and did not differ across the two anesthetics used (kx during = 0.18, iso during = 0.1611; kx after = 0.24, iso during = 0.25).
