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General anesthesia research: aroused from a deep sleep?

Nature Neuroscience volume 5, pages 928–929 (2002)Cite this article

A region of the hypothalamus that is critical in controlling sleep/wake states is now shown to mediate the sedative effects of anesthetics that act at the GABAA receptor.

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Figure 1: A simplified diagram showing some of the major connections of the tuberomammillary nucleus (TMN) and how it is involved in arousal pathways.

Rebecca Henretta

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Authors and Affiliations

  1. Department of Anesthesiology, C.V. Starr Laboratory of Molecular Neuropharmacology, Weill Medical College of Cornell University, New York, 10021, New York, USA

    Neil L. Harrison

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  1. Neil L. Harrison
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Harrison, N. General anesthesia research: aroused from a deep sleep?. Nat Neurosci 5, 928–929 (2002). https://doi.org/10.1038/nn1002-928

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