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A new link between pesticides and Parkinson's disease

Nature Neuroscience volume 3, pages 1227–1228 (2000)Cite this article

Environmental factors are thought to be an important cause of Parkinson's disease. A new study shows that rats chronically treated with the mitochondrial inhibitor rotenone, a common pesticide, develop neuropathological and behavioral symptoms of Parkinsonism.

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Figure 1: Possible mechanisms of selective cell death in Parkinson's and related diseases.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, 19104, Pennsylvania, USA

    Benoit I. Giasson & Virginia M.-Y. Lee

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  1. Benoit I. Giasson
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  2. Virginia M.-Y. Lee
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Giasson, B., Lee, VY. A new link between pesticides and Parkinson's disease. Nat Neurosci 3, 1227–1228 (2000). https://doi.org/10.1038/81737

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