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Acute coronary syndromes

Use of antipsychotic drugs linked with risk of MI

Nature Reviews Cardiology volume 13, page 442 (2016)Cite this article

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The adverse cardiovascular effects of antipsychotic treatment are well documented, but whether antipsychotic agents can increase the risk of myocardial infarction (MI) remains unclear. Yu et al. performed a systematic review and meta-analysis of nine observational studies comparing the incidence of MI in patients receiving antipsychotic drugs with those who were not receiving treatment. Patients receiving antipsychotic drugs had a 1.88-fold higher risk of developing MI than untreated individuals. Furthermore, short-term use of antipsychotic medication (<30 days) was associated with an even greater risk of MI.

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References

  1. Yu, Z. et al. Use of antipsychotics and risk of myocardial infarction: a systematic review and meta-analysis. Br. J. Clin. Pharmacol. http://dx.doi.org/10.1111/bcp.12985 (2016)

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  1. Karina Huynh
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Huynh, K. Use of antipsychotic drugs linked with risk of MI. Nat Rev Cardiol 13, 442 (2016). https://doi.org/10.1038/nrcardio.2016.92

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