Table 2 Cost-effectiveness sensitivity analysis

From: The value of single-pathogen antibacterial agents

Variable (range)

Range of variable in sensitivity analysis

US cost per QALY

Global cost per QALY

Cost of therapy per course

$3,000–$30,000

−$11,403 to $44,846

−$4,052 to $52,197

Direct health-care cost of resistance per case (United States)

$0–$26,913

$20,833 to −$7,201

$20,833 to $4,472

Ratio of global costs to US health-care costs

0.1–0.6

NA

$14,206 to $8,081

Percent of health-care cost recovered with effective therapy

25–75%

$12,007 to −$5,646

$15,682 to $5,380

Excess mortality attributable to ineffective therapy

1–30%

$63,604 to $2,120

$210,619 to $7,021

Excess mortality reduction with effective therapy

25–75%

$6,360 to $2,120

$21,062 to $7,020

Average life years gained with effective therapy per patient

4–16

$6,360 to $1,590

$21,062 to $5,265

Average quality of life per year gained

0.5–0.8

$3,816 to $2,385

$12,637 to $7,898

  1. NA, not applicable; QALY, quality-adjusted life year.
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