Table 2 Cost-effectiveness sensitivity analysis
Variable (range) | Range of variable in sensitivity analysis | US cost per QALY | Global cost per QALY |
|---|---|---|---|
Cost of therapy per course | $3,000–$30,000 | −$11,403 to $44,846 | −$4,052 to $52,197 |
Direct health-care cost of resistance per case (United States) | $0–$26,913 | $20,833 to −$7,201 | $20,833 to $4,472 |
Ratio of global costs to US health-care costs | 0.1–0.6 | NA | $14,206 to $8,081 |
Percent of health-care cost recovered with effective therapy | 25–75% | $12,007 to −$5,646 | $15,682 to $5,380 |
Excess mortality attributable to ineffective therapy | 1–30% | $63,604 to $2,120 | $210,619 to $7,021 |
Excess mortality reduction with effective therapy | 25–75% | $6,360 to $2,120 | $21,062 to $7,020 |
Average life years gained with effective therapy per patient | 4–16 | $6,360 to $1,590 | $21,062 to $5,265 |
Average quality of life per year gained | 0.5–0.8 | $3,816 to $2,385 | $12,637 to $7,898 |