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Pediatrics

Liver transplantation in very small recipients

Nature Reviews Gastroenterology & Hepatology volume 8, pages 606–607 (2011)Cite this article

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Pediatric liver transplantation is a major surgical challenge, especially in very small patients (≤5 kg), and existing literature on low-body-weight transplant recipients is limited. Two new studies discuss the possibilities and limitations of liver transplantation in very young infants and demonstrate encouraging results for liver transplantation in infancy.

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References

  1. Arnon, R. et al. Liver transplantation in children weighing 5 kg or less: Analysis of the UNOS database. Pediatr. Transplant. 15, 650–658 (2011).

    PubMed  Google Scholar 

  2. Gelas, T. et al. ABO-incompatible pediatric liver transplantation in very small recipients: Birmingham's experience. Pediatr. Transplant. 10.1111/j.1399–30462011.01541.x.

  3. Grabhorn, E. et al. Short-and long-term results of liver transplantation in infants aged less than 6 months. Transplantation 78, 235–241 (2004).

    Article  Google Scholar 

  4. Sundaram, S. S., Alonso, E. M. & Anand, R. Outcomes after liver transplantation in young infants. J. Pediatr. Gastroenterol. Nutr. 47, 486–492 (2008).

    Article  Google Scholar 

  5. Sundaram, S. S., Alonso, E. M., Narkewitz, M. R., Zhang, S. & Squires, R. H. Characterization and outcomes of young infants with acute liver failure. J. Pediatr. 10.1016/j.jpeds.2011.04.016.

  6. Schulze, M. et al. Implications for the usage of the left lateral liver graft for infants <10 kg, irrespective of a large-for-size situation—are monosegmental grafts redundant? Transpl. Int. 24, 797–804 (2011).

    Article  Google Scholar 

  7. Raut, V. & Uemoto, S. Management of ABO-incompatible living-donor liver transplantation: past and present trends. Surg. Today 41, 317–322 (2011).

    Article  CAS  Google Scholar 

  8. Tanabe, M. et al. Current progress in ABO-incompatible liver transplantation. Eur.J. Clin. Invest. 40, 943–949 (2010).

    Article  Google Scholar 

  9. Wu, J. et al. Recipient outcome after ABO-incompatible liver transplantation: a systematic review and meta-analysis. PloS ONE 6, e16521 (2010).

    Article  Google Scholar 

  10. McDiarmid, S. V., Anand, R., Martz, K., Millis, M. J. & Mazariegos, G. A multivariate analysis of pre-, peri-, and post-transplant factors affecting outcome after pediatric liver transplantation. Ann. Surg. 254, 145–154 (2011).

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatric Hepatology and Liver Transplantation, University Medical Center Hamburg Eppendorf, Martinistrasse 52, Hamburg, 20246, Germany

    Rainer Ganschow

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  1. Rainer Ganschow
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The author declares no competing financial interests.

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Ganschow, R. Liver transplantation in very small recipients. Nat Rev Gastroenterol Hepatol 8, 606–607 (2011). https://doi.org/10.1038/nrgastro.2011.190

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