Abstract
This month's Genome Watch highlights how single-cell transcriptomic analysis of infected macrophages has provided insight into the diversity in host–pathogen interactions.
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References
Claudi, B. et al. Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy. Cell 158, 722–733 (2014).
Avraham, R. et al. Pathogen cell-to-cell variability drives heterogeneity in host immune responses. Cell 162, 1309–1321 (2015).
Jorth, P. et al. Regional isolation drives bacterial diversification within cystic fibrosis lungs. Cell Host Microbe 18, 307–319 (2015).
Lieberman, T. D. et al. Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. Nat. Genet. 46, 82–87 (2014).
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David, S., Hadfield, J. It's diversity all the way down. Nat Rev Microbiol 13, 740 (2015). https://doi.org/10.1038/nrmicro3587
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DOI: https://doi.org/10.1038/nrmicro3587