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Transplantation

Promising outcomes of HIV-positive-to-HIV-positive kidney transplantation

Nature Reviews Nephrology volume 11, page 197 (2015)Cite this article

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Transplantation of kidneys from HIV-positive donors is “an additional treatment option” for HIV-positive patients who require renal replacement therapy, suggest Elmi Muller and colleagues. In their new paper, these researchers report the medium-term outcomes of HIV-positive-to-HIV-positive kidney transplantation in Groote Schuur Hospital, South Africa.

Among 27 HIV-positive recipients of kidneys from HIV-positive donors, cumulative patient survival was 84% at 1 year and at 3 years, decreasing to 74% at 5 years; graft survival was 93% at 1 year and 84% at 3 years and at 5 years. Rates of graft rejection were 8% at 1 year and 22% at 3 years. Importantly, plasma HIV load did not increase after transplantation.

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References

  1. Muller, E. et al. HIV-positive-to-HIV-positive kidney transplantation—results at 3 to 5 years. N. Engl. J. Med. 372, 613–620 (2015)

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  1. Ellen F. Carney
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Carney, E. Promising outcomes of HIV-positive-to-HIV-positive kidney transplantation. Nat Rev Nephrol 11, 197 (2015). https://doi.org/10.1038/nrneph.2015.23

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