Supplementary Figure 3: Cell-type-specific genes are misregulated after HSP90 inhibition.
From: The evolutionary capacitor HSP90 buffers the regulatory effects of mammalian endogenous retroviruses
(a,b) Highly tissue-specific genes are ectopically activated in NPCs (a) and macrophages (b) upon HSP90 inhibition due to their neighborhood to ERVs. The heat maps were generated using RNAseq data from ENCODE detailing gene expression patterns in each of the individual mouse tissues. (c,d) Genes in (a) and (b) respectively are clustered together by common gene ontology terms as depicted.
