Figure 6
From: The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1
EGR1 overexpression regulates the transcription of genes independently of ALK inhibition. (a) Heat map of gene expression signature in response to ALK and/or EGFR inhibition in H2228 cells and in H2228 cells overexpressing EGR1. The color scale bar represents relative gene expression changes calculated as log2 (inhibited/non-inhibited). (b) List and expression changes of genes up- or downregualated by the overexpression of EGR1 independently of ALK or EGFR inhibition.
