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Primary Care Respiratory Journal
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Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome: a pilot study
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  • Brief Communication
  • Published: 22 March 2011

Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome: a pilot study

  • Kazuhiko Kotani1,2,3,
  • Satoshi Kimura4,
  • Ichiro Komada5,
  • Naoki Sakane1 &
  • …
  • Alejandro Gugliucci2 

Primary Care Respiratory Journal volume 20, pages 336–337 (2011)Cite this article

  • 696 Accesses

  • 5 Citations

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Abstract

Nasal continuous positive air pressure (nCPAP) treatment may favourably affect serum levels of advanced glycation end products (AGEs) in patients with obstructive sleep apnoea syndrome (OSAS). At baseline, OSAS patients had significantly higher levels of AGEs than controls. Six months after nCPAP initiation, AGEs decreased significantly. nCPAP treatment could lower AGEs in patients with OSAS.

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Authors and Affiliations

  1. Division of Preventive Medicine, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan

    Kazuhiko Kotani & Naoki Sakane

  2. Glycation, Oxidation and Disease Laboratory, Touro University-California, Vallejo, CA, USA

    Kazuhiko Kotani & Alejandro Gugliucci

  3. Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke-City, Tochigi, Japan

    Kazuhiko Kotani

  4. Department of Clinical Laboratory, Showa University Northern Yokohama Hospital, Yokohama-City, Japan

    Satoshi Kimura

  5. Department of Otorhinolaryngology, Shiga Hospital of Social Insurance, Shiga, Japan

    Ichiro Komada

Authors
  1. Kazuhiko Kotani
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  2. Satoshi Kimura
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  3. Ichiro Komada
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  4. Naoki Sakane
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  5. Alejandro Gugliucci
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Corresponding author

Correspondence to Kazuhiko Kotani.

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Competing interests

There are no conflicts of interest in relation to the research presented.

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Cite this article

Kotani, K., Kimura, S., Komada, I. et al. Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome: a pilot study. Prim Care Respir J 20, 336–337 (2011). https://doi.org/10.4104/pcrj.2011.00021

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  • Received: 27 April 2010

  • Revised: 18 November 2010

  • Accepted: 28 December 2010

  • Published: 22 March 2011

  • Issue date: September 2011

  • DOI: https://doi.org/10.4104/pcrj.2011.00021

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This article is cited by

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    Journal of Human Hypertension (2015)

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Primary Care Respiratory Journal (Prim Care Respir J)

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