Abstract
Studies were made on the conformational changes of poly(L-ornithine) (PLO) by interaction with sulfated poly(vinyl alcohol)s (PVS) as functions of pH, temperature, the degree of sulfation and the composition of the polymeric moieties. Polymer–polymer interaction took place below ca. pH 10.6, while no interaction of PLO with PVS was found at ca. pH 12.0. PLO took on a random coil conformation through complex formations with PVS-25 and PVS-30 (the number indicates the degree of sulfation in mol %) at low pHs. In these complexes with PVS-46 and PVS-95, the α-helix and the β2-form of PLO were formed at 1.5°C in the acidic pH region and in the pH region from ca. 8.8 to ca. 10.5, respectively. The conformation of PLO in the complexes is also discussed in terms of the free-energy change resulting from the conformational change from random coil to the α-helix.
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References
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Cho, C., Komoto, T. & Kawai, T. Interaction between Poly(L-ornithine) and Sulfated Poly(vinyl alcohol). Polym J 12, 71–77 (1980). https://doi.org/10.1295/polymj.12.71
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DOI: https://doi.org/10.1295/polymj.12.71
