Abstract
Extract: Thoracic gas volume (TGV), specific compliance (SC), and mean pulmonary resistance were measured in 38 healthy infants between 4 and 46 weeks of age. TGV had a mean value of 30±3.3 ml/kg of body weight or 0.768±0.089 × 10-3 ml/cm body length3. The mean value for SC was 0.056±0.01 cm H2O/l TGV; that for specific pulmonary conductance was 0.298±0.075 1/sec/cm H2O/TGV. Pulmonary conductance related to body length3 had a mean value of 0.221±0.066 × 10-6 1/sec/cm H2O/cm3. The value for the change in intraesophageal pressure between the minimum and maximum values in each respiratory cycle was 8.0±1.47 cm H2O.
The results of this study indicate that TGV, SC, and pulmonary resistance, when related to body size, show little difference when comparing newborn infants and adults.
Speculation: Measurements of respiratory function in infants are known to be practical. The availability of such measurements in healthy infants should make possible the determination of abnormalities in the respiration of infants with acute viral bronchiolitis and cystic fibrosis of the pancreas, or other respiratory diseases.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Phelan, P., Williams, H. Ventilatory Studies in Healthy Infants. Pediatr Res 3, 425–432 (1969). https://doi.org/10.1203/00006450-196909000-00005
Issue date:
DOI: https://doi.org/10.1203/00006450-196909000-00005
Keywords
This article is cited by
-
Respiratory system compliance at the same PEEP level is similar in COVID and non-COVID ARDS
Respiratory Research (2022)
-
Practical interest in the detection of functional abnormalities in infants and children with lung disease
European Journal of Pediatrics (1993)
