Abstract
Recent reports have suggested a correlation between a positive antibody coated bacteria test (ACBT) and urinary tract infection (UTI) of renal origin. Studies were performed to observe whether a relationship between a + ABCT and recurrent UTI exist. A total of 34 tests were performed in 16 children with significant bacteriuria (ages 3 1/2-12 yrs, M-4, F-12). Twelve of 16 children had E. coli infection. Duration of treatment was 6 wks or longer in 13 and 2 wks in 3 children. Radlologic examination demonstrated no anatomical defect in 14 of 16 children. Follow-up was 4-14 mos. Renal tissue examined from a child with + ACBT showed changes consistent with chronic pyelonephritis, however, antibody coated bacteria was not demonstrated. In 2 untreated children with 17 recurrences sequential ACBT demonstrated alternating + or - results. The recurrence rate and the results of the ACBT are tabulated.
The recurrence rate in patients with + ACBT was not significantly different from those with - ACBT. The recurrence rate in UTI can not be predicted by the results of ACBT.
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Tina, L., Jimenez, C., Papadopoulou, Z. et al. ANTIBODY COATED BACTERIA IN RECURRENT URINARY TRACT INFECTION. Pediatr Res 11, 508 (1977). https://doi.org/10.1203/00006450-197704000-00831
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DOI: https://doi.org/10.1203/00006450-197704000-00831