Abstract
Pituitary function was studied in four pairs of familial pituitary dwarfs (two sisters 28 and 20 years old, two brothers 15 and 11 years old, one sister aged 19 and her brother aged 6 and one sister aged 9 6/12 and her brother 3 6/12), by performing 1-dopa test, TRH-test ,LHRH-test, sulpiride-test and by measuring basal concentrations of ACTH and Cortisol (F). It was found that all patients had abnormal responses of GH to 1-dopa test, and of prolactin to sulpiride-test but there was an intra-and interfamilial variability as regards the response of TSH to TRH, of FSH and LH to LHRH and the basal levels of ACTH and F.
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Batrinos, M., Pitoulis, S., Anousakis, C. et al. Pituitary function in 8 patients with familial pituitary dwarfism. Pediatr Res 12, 1095 (1978). https://doi.org/10.1203/00006450-197811000-00084
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DOI: https://doi.org/10.1203/00006450-197811000-00084
