Abstract
The aim of this study was to verify whether exaggerated natriuresis is always present after PSAGN,as previously reported.Nine patients(7 children,2 adults) two years after PSAGN and four healthy control subjects(3 adults,1child) were studied.All subjects had normal urinalysis,GFR and BP.Following two control periods of 30 min(I,II) an i.v. saline load (2.5%NaCl, 1L/1.73m2) was given over 45 min(III).GFR,UVna and venous HTC were measured during these periods as well as during four 30 min collection periods following completion of the saline load (IV,V,VI,VII).
GFR was comparable in the two groups.No significant differences were found in absolute or fractional excretion of sodium.We thus found no evidence for exaggerated natriuresis two years after PSAGN.We conclude that PSAGN as seen by us in Israel, carries a good (short-term) clinical and renal functional prognosis.
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Drukker, A., Shaull, S., Erlichman, M. et al. I.V. SALINE LOADING AFTER ACUTE POST-STREPTOCOCCAL GLOMERULONEPHRITIS (PSAGN). Pediatr Res 14, 989 (1980). https://doi.org/10.1203/00006450-198008000-00096
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DOI: https://doi.org/10.1203/00006450-198008000-00096
