Abstract
ST of AP lip. ext. measures fetal pulmonic maturity. A high ST of AF collected ⩽24 hrs prior to delivery appears to us to be a nonspecific marker of high risk newborn. AF lipid extracted by chloroform methanol mixture was added to water until maximal decrease of surface tension was reached. The sum of microliters of extract and dynes/cm of surface tension reduction was expressed as an ST “sum”. The ST sum was correlated with clinical progress of the baby.
We studied AF from 59 mothers. Twenty of the 59 babies had a complications(s) (hypoglycemia 6, neconium staining 5, Rh disease 4, ABO incompatibility 3, multiple congenital abnormalities 1,RDS1).
ST sum of >40 was found in 75% of babies with complications. Low gestation age (<37 wks) identifies 40% and low birth wt. (<2500 gm) only 15% of the 20 babies with complications. The predictive value (for complications) of the ST sum is signficantly greater than that of using low gestation age (p <.02) or of low birth wt (p <.01) as a criterion.
Conclusion: ST sum of >40 suggests an abnormal course in immediate neonatal period requiring close observation.
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Tiwary, C., Landes, R., Haddock, J. et al. 1452 SURFACE TENSION (ST) OF AMNIOTIC FLUID (AF) LIPID EXTRACT (LIP. EXT.) AS A PREDICTOR OF IMMEDIATE NEONATAL COURSE. Pediatr Res 15 (Suppl 4), 685 (1981). https://doi.org/10.1203/00006450-198104001-01481
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DOI: https://doi.org/10.1203/00006450-198104001-01481
