Abstract
In the critical care of children it is increasingly necessary to use total parenteral nutrition. Daily intakes of fluids, calories (amino acids, dextrose, fat), minerals and vitamins were prospectively monitored in 17 sick children aged 6 mos. to 14 years during 24 episodes of total parenteral nutrition (TPN). Essential laboratory observations were also prospectively made. Twelve children had one, 3 had two and 2 had three episodes of TPN administrations. Duration of TPN for children weighing less than 10 kg was 13±3 days (mean ±SD) and for those over 10 kg, it was 10±2 days (mean ± SD). To maintain normal serum electrolytes, mean daily intakes for most minerals remained constant throughout TPN administration, except for sodium and chloride where the mean daily requirements decreased from 4.0 and 4.4 meq/kg respectively to 2.6 and 2.8 meq/kg respectively at 10-12 days. Moderate elevations in values of SGOT/SGPT were observed in most patients between 7 and 10 days and LDH and CPK between 17 to 20 days of treatment. Significant biphasic elevations in blood sugar was noted at days 5 to 7 and days 18 to 21, when the mean blood sugar rose from 100 mg/dl to 147 mg/dl and 132 mg/dl respectively. The mean daily requirements for fluids, calories and vitamins did not change significantly once optimal intakes have been achieved. In 3 children, serum levels of magnesium, zinc and copper were carefully monitored and no changes were found.
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Adebonojo, F. 607 NUTRIENT CHANGES IN CRITICALLY ILL CHILDREN ON TOTAL PARENTERAL NUTRITION. Pediatr Res 19, 212 (1985). https://doi.org/10.1203/00006450-198504000-00637
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DOI: https://doi.org/10.1203/00006450-198504000-00637
