Abstract
Our purpose was to compare nutrient balance between a PHW and a non-hydrolysed casein/whey (NHCW) formula. Infants (birthweight ≤ 1750 g, gestation ≤ 32 weeks, postnatal age 15 - 59 days) tolerating an enteral intake ≥ 100 cals/kg/d with a weight gain ≥ 15 g/d were studied. Infants were fed both formulas in a balanced random fashion. After a period of 4 days a 48-hour balance was done. Results were analysed using a paired t-test and considered significant at <.05. Nitrogen (N) intake (572 ± 58 v 503 ± 48 mg/kg/d), absorption (490 ± 60 v 453 ± 63) and retention (381 ± 55 v 369 ± 60) were not different. Stool (82 ± 18 v 49 ± 23; p<.01) and urinary (109 ± 76 v 84 ± 38; p,.10) N excretion tended or were greater, while % N absorption (86 ± 4 v 90 ± 6; p<.01), and retention (66 ± 4 v 73 ± 5; p = .06) tended or were less with the PHW formula. Fat and calcium balance were not different. Further analyses indicated that N and fat absorption were affected by postconceptional age and calcium absorption by postnatal age. These findings suggest that N assimilation is not greater with a PHW protein and that immaturity is a confouding variable in the interpretation of balance studies in the preterm infant.
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Cooke, R., Rosgilly, L. & Wareham, P. 52 NUTRIENT BALANCE IN PRETERM INFANTS FED A PARTIALLY HYDROLYSED WHEY (PHW) INFANT FORMULA. Pediatr Res 36, 11 (1994). https://doi.org/10.1203/00006450-199407000-00052
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DOI: https://doi.org/10.1203/00006450-199407000-00052
