Abstract
Dual energy X Ray absorptiometry (DXA) is a non invasive, accurate and precise method for assessing BMCt and body composition in infants. 25 VLBW infants were studied by DXA at 3 months (theoretical term) and 6 months of age and were compared to normal values obtained in full term (FT) newborns. Mean birthweight ± SD was 1185 ± 151 g and mean gestational age ± SD was 30.6 ± 2 weeks. They were divided into 2 groups according to the diet: human milk (HM) + fortifier (n = 10), and LBW formula (n = 15). Results of scans are expressed in mean ± SD.
Conclusions: (1) In VLBW infants, at 3 months of age, BMCt was significantly lower than in FT newborns at birth (66 g) and thus demonstrated osteopenia. On the contrary at 6 months such a difference was not found anymore. (2) Body composition at 3 months was not significantly different of that of FT newborns at birth; but al 6 months fat content was elevated. (3) Diet did not influence body composition and BMCt in VLBW infants as measured at 3 and 6 months.
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Lapillonne, A., Salle, B., Glorieux, F. et al. 122 LONGITUDINAL STUDY OF WHOLE BONE MINERAL CONTENT (BMCt) AND BODY COMPOSITION IN VERY LOW BIRTHWEIGHT (VLBW) INFANTS. Pediatr Res 36, 23 (1994). https://doi.org/10.1203/00006450-199407000-00122
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DOI: https://doi.org/10.1203/00006450-199407000-00122