Decreased endothelium dependent arterial dilation to reactive hyperemia has been shown in adults to be associated with various manifestations of cardiovascular (CV) diseases and cardiovascular risk factors. In a sample of children we examined the relationships between flow-mediated femoral artery dilation and anthropometric, demographic, and CV parameters which have been associated with CV diseases.

Participants. 33 asymptomatic, healthy 11-14 years olds randomly selected from participants in a longitudinal CV health study. There were 17 boys and 16 girls; 21 Whites and 12 Blacks. Sixteen had documented family history of premature myocardial infarction (i.e.,≤55 yrs of age) and 17 did not.

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