Purpose: This prospective, open, randomized, parallel, multicenter study compared fat absorption (ABS) & N, Ca, P and Mg absorption and retention (RET) in two cow's milk based term infant formulas, a lactose free (L-) and a marketed lactose containing (L+) formula. Both were identical except for lactose (L+:100%; L-:0%), calcium (L+:420 mg/L; L-:550 mg/L), & phosphorus (L+:280 mg/L; L-:366 mg/L) content. L- protein was slightly more processed to reduce lactose.

Methods: Following a 4-7 day formula feeding equilibration, urine& stool were collected during a 72 hour metabolic balance. These outputs& formula were analyzed for N, Ca, P & Mg. Stools & formula were also analyzed for fat content. No medication, mineral supplements or solid food was permitted during the study. Weight was measured at the start & end of the metabolic balance.

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