Table 1 SARS-CoV-2-derived T cell epitopes predicted with high affinity to HLA molecules
From: Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2
Protein | Length of protein (amino acids) | Number of epitopes | |||||||
|---|---|---|---|---|---|---|---|---|---|
HLA-class I epitopes (rank ≤ 0.5%) | HLA-class II epitopes (rank ≤ 2%) | ||||||||
All | HLA-A | HLA-B | HLA-C | All | HLA-DP | HLA-DQ | HLA-DR | ||
ORF1ab | 7096 | 1478 | 665 | 937 | 588 | 1002 | 268 | 377 | 572 |
S | 1273 | 248 | 105 | 159 | 110 | 154 | 48 | 54 | 88 |
ORF3a | 275 | 69 | 30 | 48 | 28 | 74 | 33 | 25 | 46 |
E | 75 | 18 | 11 | 11 | 5 | 11 | 3 | 0 | 11 |
M | 222 | 72 | 36 | 35 | 25 | 57 | 16 | 21 | 35 |
ORF6 | 61 | 8 | 4 | 4 | 2 | 28 | 10 | 12 | 13 |
ORF7a | 121 | 26 | 11 | 18 | 9 | 16 | 10 | 0 | 6 |
ORF8 | 121 | 22 | 11 | 14 | 10 | 18 | 4 | 10 | 8 |
N | 419 | 60 | 21 | 35 | 21 | 32 | 4 | 17 | 12 |
ORF10 | 38 | 12 | 4 | 10 | 7 | 7 | 7 | 0 | 0 |
Total | Â | 2013 | 898 | 1271 | 805 | 1399 | 403 | 516 | 791 |
