Table 4 Mutations frequently (≥10%) observed in SARS-CoV-2 isolated from four different regions

From: Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2

Protein

Position in protein

Reference amino acida

Mutant amino acid

Mutation frequency

Asia (N = 587)

North America (N = 1918)

Europe (N = 3190)

Oceania (N = 726)

ORF1ab

265

T

I

0.0346

0.424

0.104

0.171

ORF1ab

3606

L

F

0.248

0.0438

0.178

0.17

ORF1ab

4715

P

L

0.154

0.587

0.737

0.526

ORF1ab

5828

P

L

0

0.306

0.00599

0.0783

ORF1ab

5865

Y

C

0

0.314

0.00530

0.0805

S

614

D

G

0.155

0.586

0.736

0.526

ORF3a

57

Q

H

0.0426

0.489

0.142

0.204

ORF3a

251

G

V

0.0991

0.0256

0.172

0.121

ORF8

84

L

S

0.222

0.351

0.0295

0.206

N

13

P

L

0.0171

0.00313

0.00126

0.105

N

203

R

K

0.0532

0.0365

0.276

0.148

N

204

G

R

0.0532

0.0355

0.276

0.147

  1. aProtein sequence based on the reference SARS-CoV-2_Wuhan-Hu-1 sequence (GenBank accession number MN908947)