Table 2 Accuracy measures for classification of ovarian tumors by BRCA status using DNA methylation data

From: Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature

Accuracy indicator

Fold 1

Fold 2

Fold 3

Fold 4

Fold 5

Average

Overall accuracy

0.69

0.81

0.81

0.71

0.73

0.75

Sensitivity

0.67

0.89

0.89

0.8

0.89

0.83

Specificity

0.71

0.71

0.71

0.57

0.5

0.64

PPV

0.75

0.8

0.8

0.73

0.73

0.76

NPV

0.62

0.83

0.83

0.67

0.75

0.74

AUC

0.68

0.79

0.79

0.8

0.78

0.77