Fig. 4
From: Heritability of complex traits in sub-populations experiencing bottlenecks and growth
The distribution of heritability of a bottlenecked population as observable in a GWAS study against simulated heritability present, over 200 repeated experiments. a the simulated heritability distribution (yellow) and observed thresholded heritability (green) where only the 1/29 percentile of most informative SNPs (by VE = variance explained) are observed. b Comparing heritability when thresholding on p-values over 200 repeated experiments, where the threshold heritability only captures the t = 1/2n most extreme SNPs. The red line depicts values such that simulated and threshold heritability are equal. c as b, but where SNPs are ranked by variance explained. d Pearson correlation and regression coefficient between the real heritability and threshold heritability for thresholds t = 1/2n with standard error bars
