Fig. 1: Genetic testing-related distress (IES-R) according to the background characteristics of the participants. | Journal of Human Genetics

Fig. 1: Genetic testing-related distress (IES-R) according to the background characteristics of the participants.

From: Psychological distress and cancer worry in unaffected relatives undergoing cascade testing with multigene panel testing

Fig. 1: Genetic testing-related distress (IES-R) according to the background characteristics of the participants.The alternative text for this image may have been generated using AI.

IES-R scores were presented as background factors among cancer-unaffected first-degree relatives of individuals with hereditary cancer. IES-R scores were collected two weeks after the disclosure of test results. All results are shown as mean. a Genetic test result categories in the BRANCH study (p = 0.1386). (GPV, germline pathogenic variant; VUS, variant of uncertain significance). b Pre-disclosure (T0) cancer worry levels assessed using the Japanese version of the Cancer Worry Scale (CWS-J) and categorized as low (<13) and high (≥14) (p < 0.001). c Frequency of discussions with family regarding cancer risk (p < 0.05, univariate analysis). d Relationship with the proband (p = 0.0552)

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