Fig. 5: Tau pathology correlates with sCD44 distribution.
From: Glioblastoma-secreted soluble CD44 activates tau pathology in the brain
a Distribution of intracellular CD44 (iCD44) and soluble CD44 (sCD44) in the U87-xenograft brain tissue. Scale bar, 2 mm. b Fluorescence intensity profiles of iCD44 and sCD44 along the dashed line of the tissue section in a. Based on the intensity profiles, five regions (labeled from i to v) were selected. c CD44 and tau immunofluorescence images of the five selected regions. U87-xenograft brain tissue was immunofluorescence stained with anti-iCD44, anti-sCD44, and anti-AT8 antibodies. Scale bar, 100 µm
