Fig. 1: Effect of exendin-4 on fibrosis in HG-induced HK-2 cells. | Experimental & Molecular Medicine

Fig. 1: Effect of exendin-4 on fibrosis in HG-induced HK-2 cells.

From: Exendin-4 ameliorates high glucose-induced fibrosis by inhibiting the secretion of miR-192 from injured renal tubular epithelial cells

Fig. 1

HK-2 cells were cultured in DMEM with 5.6 mM glucose (NG) or 30 mM glucose (HG) and different concentrations of exendin-4. a–f Relative expression of FN and Col-I in HK-2 cells after incubation with HG and various concentrations of exendin-4 for 24, 48, and 72 h. g, h FN and Col-I expression in HK-2 cells after incubation with HG and 10 nM exendin-4 for 48 h was analyzed by western blot (**P < 0.01 and ***P < 0.001 versus the NG group; #P < 0.05,##P < 0.01, and ###P < 0.001 versus the HG group)

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