Fig. 6: Parallel changes in the overexpression of EGFR, hnRNP Q1, Aurora-A and spindle assembly checkpoint genes in colorectal cancer tissues. | Experimental & Molecular Medicine

Fig. 6: Parallel changes in the overexpression of EGFR, hnRNP Q1, Aurora-A and spindle assembly checkpoint genes in colorectal cancer tissues.

From: The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Fig. 6

a Western blot analysis was used to determine the expression levels of the EGFR, hnRNP Q1, Aurora-A, Mad2, Bub1, BubR1, and Mps1 proteins in human colorectal tumors (T) and adjacent normal colon mucosal tissues (N). Six representative specimens (P1–P6) are shown. b The expression levels of the Mad2, Bub1, BubR1, and Mps1 mRNAs in human colorectal cancer tissues (T) and their normal colon mucosal tissues (N) were analyzed using RT-qPCR. (N = 40; *p < 0.05; **p < 0.01; ***p < 0.001)

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