Table 2 ELISA confirms LDH, TNF-α, and IL-1β are increased in mice with I/R injury after TKA

From: RETRACTED ARTICLE: Downregulation of the long noncoding RNA MBNL1-AS1 protects sevoflurane-pretreated mice against ischemia-reperfusion injury by targeting KCNMA1

Group

TNF-α (ng/L)

IL-1β (ng/L)

LDH (U/L)

Normal

35.13 ± 2.43

68.74 ± 4.25

201.83 ± 11.43

I/R

98.16 ± 8.92*

187.13 ± 8.27*

458.62 ± 25.52*

Sevo

67.53 ± 5.14*#

146.26 ± 7.42*#

314.27 ± 21.52*#

  1. I/R ischemia-reperfusion, Sevo sevoflurane, LDH lactic dehydrogenase, TNF-α tumor necrosis factor-α, IL-1β interleukin-1β, ELISA enzyme-linked immunosorbent assay
  2. *p < 0.05 vs. the normal group; # p  < 0.05 vs. the I/R group; n = 10; measurement data were expressed as mean ± standard deviation and comparisons among multiple groups were assessed by one-way ANOVA; the experiment was repeated for 3 times