Fig. 2: Effects of USP15 RNA-interference and USP15 overexpression on MM cell proliferation.

After RPMI 8226 and U266 cells were transfected with siNC plus empty pLVX-Puro (vector), siUSP15#1, siUSP15#2, or pLVX-Puro-USP15, the expression of USP15 was measured by western blot (a–d) and cell proliferation was measured by the CCK-8 assay (e, f). ***P < 0.001 compared with siNC, vector or vector + siNC