Fig. 6: IM stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth. | Experimental & Molecular Medicine

Fig. 6: IM stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth.

From: A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming

Fig. 6: IM stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth.The alternative text for this image may have been generated using AI.

Immunohistochemistry of K15, PDK, Ki67, and PDH in each treated mouse skin on a day 7 and b day 20. DAPI staining was used to identify the nuclei (blue). Scale bar = 50 μm. c FACS analysis of K15/PDK and Ki67/PDH in single cells of each treated mouse skin on day 7. d Expression of the indicated gene in each treated mouse was quantified by real-time PCR analysis on days 7 and 20 after depilation. β-Actin expression was used as an internal control. *p < 0.05; **p < 0.01; ***p < 0.001 (Student’s t-test)

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