Table 1 Transcriptomics of pathological condition-derived EVs
From: Systems biology approaches to investigating the roles of extracellular vesicles in human diseases
Disease/pathological condition | Biological fluid | EV transcriptomics | Applied methods | Publication |
|---|---|---|---|---|
Mycobacterium tuberculosis Infection | Serum | mRNA, miRNA, snRNA, snoRNa, ncRNA, | RNA-Seq | |
Hand, foot, and mouth disease | Serum | miRNA | Human miRNA microarray | |
Type 1 diabetes mellitus | Urine | miRNA | RNA-Seq | |
Type 2 diabetes mellitus | Plasma | miRNA | Focus miRNA PCR panel | |
Heart failure after acute myocardial infarction | Serum | miRNA | miRNA microarray | |
Prostate cancer | Urine | mRNA | Whole-genome gene expression direct hybridization | |
Benign prostate hyperplasia | Urine | mRNA | Whole-genome gene expression direct hybridization | |
Breast cancer | Serum | miRNA | Small RNA sequencing | |
Breast invasive lobular carcinoma | Plasma | mRNA | RNA-Seq | |
Colorectal carcinoma | Plasma and serum | miRNA | Human miRNome panels I and II (Ver.3) | |
Ovarian cancer | Plasma | RNA | Microarray analysis | |
Serous papillary adenocarcinoma of the ovary | Serum | miRNA | Microarray analysis | |
Ovarian carcinoma | Peritoneal or pleural effusion | miRNA | TaqMan microRNA array A | |
Lung adenocarcinoma | Plasma | miRNA | miRCURY-human-panel-I + II-V1.M | |
Lung adenocarcinoma | Plasma | miRNA | miRNA microarray | |
Melanoma | Vitreous humor and serum | miRNA | TaqMan low density array | |
Pancreaticobiliary cancers | Pleural fluid and plasma | mRNA | Transcriptome sequencing | |
Osteosarcoma | Plasma | mRNA, rRNA, tRNA, ncRNA | RNA-Seq | |
Glioblastoma multiforme | Serum | mRNA | Agilent 4 × 44 K human microarrays | |
Young-Onset Alzheimer’s Disease | Cerebrospinal fluid | miRNA | Human miRNome panels I + II (V4.M) | |
Multiple sclerosis | Plasma | miRNA | 3D-Gene Human miRNA oligo chip | |
Relapsing-remitting multiple sclerosis | Serum | tRNA, tRNA-like, rfam, miRNA, lincRNA, scaRNA, rRNA, piRNA, | XRNA RNA-seq | |
Cardiac allograft rejection | Serum | miRNA | Focus human microRNA PCR | |
Chronic lung allograft dysfunction | Bronchoalveolar lavage fluid | Exosomal shuttle RNA | RNA-seq | |
Oligoasthenozoospermia | Seminal plasma | miRNA | 60 K microarray | |
Salt sensitivity of blood pressure | Urine | miRNA | miRNA microarray | |
Post vasectomy | Seminal plasma | miRNA | miRNA microarray | |
Post gastric bypass surgery | plasma and serum | miRNA | miRNA microarray |
