Fig. 1: Luteolin is a potential treatment option for ischemic stroke. | Experimental & Molecular Medicine

Fig. 1: Luteolin is a potential treatment option for ischemic stroke.

From: Connectivity map identifies luteolin as a treatment option of ischemic stroke by inhibiting MMP9 and activation of the PI3K/Akt signaling pathway

Fig. 1

a Differentially expressed mRNAs were analyzed by microarray and presented on a heatmap. b Bar graph represents the connectivity score data for luteolin. The black horizontal lines represent each instance performed with the respective compound. Instances in the red area indicate negative correlation scores, and instances in the green area indicate positive ones. No correlation could be detected for instances in the gray area. The chemical structure of luteolin is also shown. c The target proteins of luteolin, MMP9, and AKT1 were identified using STITCH

Back to article page