Fig. 5: Increased hair growth in mice by amniotic fluid–derived mesenchymal stem cell overexpressing Nanog (AF-N-MSC)–derived conditioned media (AF-N-CM). | Experimental & Molecular Medicine

Fig. 5: Increased hair growth in mice by amniotic fluid–derived mesenchymal stem cell overexpressing Nanog (AF-N-MSC)–derived conditioned media (AF-N-CM).

From: Overexpression of Nanog in amniotic fluid–derived mesenchymal stem cells accelerates dermal papilla cell activity and promotes hair follicle regeneration

Fig. 5: Increased hair growth in mice by amniotic fluid–derived mesenchymal stem cell overexpressing Nanog (AF-N-MSC)–derived conditioned media (AF-N-CM).

a Schematic of a process for assessing the effect of AF-N-CM on hair regeneration. b Digital images of the dorsal skin of telogen C57BL/6 mice treated with AF-CM, AF-N-CM, or minoxidil. Stages of the hair cycle were determined by comparing dorsal skin colors. c Representative hematoxylin–eosin (H&E) images of dorsal skin sections for determination of hair follicle (HF) number and cycle. Scale bar, 200 µm. d HFs in 0.36 cm2. e H&E-stained dorsal skin section 5 days post-depilation. Scale bar, 600 µm. Data are represented as the mean ± SD (n = 3). **p < 0.01

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