Table 1 Comparison of the effects of 5-FC treatment on the time required to eliminate the CD episomal vectors
From: Efficient exogenous DNA-free reprogramming with suicide gene vectors
Cell line | 5-FC (μM) | Minimum number of passages needed for EF-cell generation |
|---|---|---|
Control-iPSC #01a | 0 | >6 |
50 | >6 | |
CD-iPSC #01a | 0 | >6 |
50 | 4 | |
CD-iPSC #02b | 0 | >1 |
50 | 1 | |
CD-iPSC #03b | 0 | >2 |
50 | 2 | |
CD-iPSC #04b | 0 | >2 |
50 | 2 | |
CD-iNSCb | 0 | >3 |
50 | 1 |