Fig. 5: HDAC9 knockdown inhibited cell colony formation and proliferation.
From: Identification of HDAC9 as a viable therapeutic target for the treatment of gastric cancer
a SGC-7901 cells transiently transfected with HDAC9-specific siRNA (siHDAC9) showed a lower colony formation capacity than cells transfected with nontargeting siRNA (siNC) or mock transfection control (mock) cells. The relative colony formation numbers were calculated by comparison with the mock group. b Silencing of HDAC9 also suppressed colony formation in BGC-823 cells. c, d The cell index parameter used to represent the number of attached viable cells was recorded in real time. The results showed a significantly lower rate of GC cell proliferation following transfection with siHDAC9 than in cells transfected with siNC and mock transfection control cells. The error bars indicate the means ± SDs; *p < 0.05, **p < 0.01 versus the control group
