Fig. 5: Mob1a/b is required for the differentiation of mouse ESCs in vivo. | Experimental & Molecular Medicine

Fig. 5: Mob1a/b is required for the differentiation of mouse ESCs in vivo.

From: Loss of Mob1a/b impairs the differentiation of mouse embryonic stem cells into the three germ layer lineages

Fig. 5: Mob1a/b is required for the differentiation of mouse ESCs in vivo.

a, b Representative images of hematoxylin and eosin staining images of a teratoma originating from Mob1af/f:Mob1bf/f:CAGGCre-ERTM ESCs. Teratomas were recovered by dissection with the surrounding tissue 6 weeks after mouse ESC injection. Scale bar, 200 μm. c Immunoblot analysis for Yap and Taz in lysates of Mob1af/f:Mob1bf/f:CAGGCre-ERTM ESCs after shYap treatment. Gapdh served as a loading control. d Representative images of immunohistochemical staining of a teratoma using an anti-Taz antibody. EC, ectodermal tissue; ME, mesodermal tissue; EN, endodermal tissue. Scale bar, 200 μm

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