Fig. 2: Rapamycin improved senescent hCPC proliferation. | Experimental & Molecular Medicine

Fig. 2: Rapamycin improved senescent hCPC proliferation.

From: Pharmacological inhibition of mTOR attenuates replicative cell senescence and improves cellular function via regulating the STAT3-PIM1 axis in human cardiac progenitor cells

Fig. 2

a Real-time cell proliferation analysis (young passage number 8; senescent passage number 18; rapamycin passage number 18). b Cell proliferation assay was detected by BrdU labeling after prolonged treatment with different concentrations of rapamycin (**p ≤ 0.01, ***p ≤ 0.001, n = 6). c Cell cycle analysis (**p ≤ 0.01, n = 0.03). d, g The expression of CENP-A from senescent hCPCs after prolonged rapamycin treatment (*p ≤ 0.05, ***p ≤ 0.001, n = 3). Error bars indicate SEM.

Back to article page