Fig. 3: The effect of rapamycin on the clonogenic potential of senescent CPCs. | Experimental & Molecular Medicine

Fig. 3: The effect of rapamycin on the clonogenic potential of senescent CPCs.

From: Pharmacological inhibition of mTOR attenuates replicative cell senescence and improves cellular function via regulating the STAT3-PIM1 axis in human cardiac progenitor cells

Fig. 3

a Clonogenic ability in senescent hCPCs after prolonged rapamycin treatment. The graph represents the percentage of wells that maintained clones for 14 days (**p ≤ 0.01, vs. young, ###p ≤ 0.001, vs. senescent). b The expression of the clonogenicity markers (OCT4, KLF4, and NANOG) was examined in senescent hCPCs after prolonged rapamycin treatment via qRT-PCR (*p ≤ 0.05). Error bars indicate SEM.

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