Table 1 Single-cell profiling of major human organs and tissues.
Systems | Organs/tissues | Notes | References |
|---|---|---|---|
Hematopoietic and immune system | Blood | Discovery of new types of blood cells | |
Hematopoietic differentiation | |||
Immune cell atlas (review) | |||
Nervous system | Brain | Transcriptional and epigenetic states | |
Human and mouse cortex | |||
Alzheimer’s disease | |||
Autism | |||
Urinary system | Kidney | Single-nucleus RNA-seq pipeline | |
Lupus nephritis | |||
Spatiotemporal immune topology | |||
Respiratory system | Lung | Lung cell atlas (review) | |
Asthma | |||
Pulmonary fibrosis | |||
Trachea | Discovery of pulmonary “ionocytes” | ||
Hepatopancreatic–biliary | Liver | Liver cell atlas | |
Pancreas | Pancreas cell atlas | ||
Gastrointestinal system | Colon | Ulcerative colitis | |
Small intestine | Crohn’s disease | ||
Cardiovascular system | Heart | Stress-related lincRNA | |
Developmental biology | Fetal kidney | Progenitor cell dynamics and lineage | |
Fetal liver | Fetal liver hematopoiesis | ||
Fetal heart | Autoimmune-associated congenital heart block | ||
Maternal–fetal interface | Trophoblast–decidual interactions | ||
Pediatric | Pediatric cell atlas (review) | ||
Reproductive system | Breast | Breast epithelial cells | |
Testis | Testis cell atlas | ||
Sensory system | Eye | Retina cell atlas |
