Table 2 List of existing and nascent single-cell genomics consortiums.
Consortium | Short name | Mission | Website | Funding source |
|---|---|---|---|---|
The Human Cell Atlas | HCA | To create comprehensive reference maps of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease | Variousa | |
Human Biomolecular Atlas Program | HuMAP | To develop an open and global platform to map healthy cells in the human body | NIH | |
Gene-Tissue Expression | GTEx | To build a comprehensive public resource to study tissue-specific gene expression and regulation | NIH | |
LifeTime Initiative | LifeTime | Revolutionizing healthcare by tracking, understanding, and treating human cells during diseases | EU (Horizon 2020) | |
The Human Protein Atlas | HPA | To map all the human proteins in cells, tissues, and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology | Knut and Alice Wallenberg Foundation (main) | |
Single-cell eQTLGen Consortium | sc-eQTLGen | To identify the upstream interactors and downstream consequences of trait-related genetic variants in specific immune cell types | Various | |
The Human Tumor Cell Atlas | HTCA | Constructing three-dimensional atlases of the cellular, morphological, and molecular features of human cancers over time | NIH/NCI | |
Allen Brain Atlas | Allen Brain Map | Accelerating progress toward understanding the brain | Philanthropic (Paul G. Allen) | |
The BRAIN initiative | Cell Census Network (BICCN) | Discovering diversity: identify and provide experimental access to the different brain cell types to determine their roles in health and disease | NIH | |
The Molecular Atlas of Lung Development Program | LungMAP | Omics, images, 3D viewer, and Analytics platform to study the human lung | NHLBI | |
Kidney Precision Medicine Program | KPMP | Purpose of understanding and finding new ways to treat chronic kidney disease (CKD) and acute kidney injury (AKI) | NIDDK | |
Immunological Genome Project | ImmGen | To computationally reconstruct the gene- regulatory network in immune cells | NIAID | |
GenitoUrinary Development Molecular Anatomy Project | GUDMAP | Focused on the kidney, lower urinary tract, and nociceptors (pain receptors), and expanding our understanding of human development of the genito-urinary system | NIDDK |