Fig. 2: Schematic diagram summarizing the similarities and differences in transcription factor expression between T-cell and ILC subtypes (NK cells/ILC1s, ILC2s, ILC3s).

T-bet promotes the differentiation of NK cells/ILC1s, while GATA3, RORα, and E4BP4 promote ILC2 differentiation, and RORγt promotes LTi cell, NCR− ILC3, and NCR+ ILC3 differentiation. Illustration created in part with BioRender.com.