Fig. 2: Epigenetic pathways inhibiting cryptic transcription.
From: Trans-tail regulation-mediated suppression of cryptic transcription

Cryptic transcriptional initiation within the ORF is suppressed by cooperation between H2Bub and the FACT complex, H3K4me2 and the histone (poly)sumoylation-mediated Set3 HDAC complex, and the H3K36me3-dependent association of the Rpd3S complex, DNMT3B, KDM5B, or FACT complex.