Fig. 3: Gene expression profiles of cell subpopulations of PBMCs in AD patients.
From: Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease
a Heat map of changes in the RNA expression of upregulated and downregulated genes in the top 6 cell types in normal people and early and late AD patients. N values below the cell names represent the cell counting results. b The gene expression changes trends of upregulated and downregulated genes in 6 different cell types. c KEGG pathway analysis of upregulated genes in 6 cell types. The heatmap was generated by the pheatmap R package, and the rows were clustered. Pearson distance measurement assigns values to the clustering rows. The line chart was generated by the ggplot R package. The bar chart of KEGG analysis was made by the hist function of R language in accordance with the -log10 (p value).
