Fig. 6: The effect of B cell depletion on Aβ deposition.
From: Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease
a Histological images of Aβ plaque distribution in the brain among the WT, AD + PBS and AD + BCDT groups. Scale bar = 20 μm and 50 μm. b Quantification data including integrated optical density (IOD) of Aβ plaque, the number of plaques and the area of plaques in WT, AD + PBS and AD + BCDT groups. c The distribution of Aβ plaques in the hippocampus (CA1, CA2, CA3, DG) among the three groups. Scale bar = 100 μm and 400 μm. d The IOD, amount and area of Aβ plaques in the four regions of the hippocampus among the three groups. WT, wild-type (mice); BCDT, B cell depletion treated.
