Fig. 4: Protection of vascular integrity by CU06-1004 promotes long-term cardiac function after I/R injury. | Experimental & Molecular Medicine

Fig. 4: Protection of vascular integrity by CU06-1004 promotes long-term cardiac function after I/R injury.

From: CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

Fig. 4

a Representative M-mode images of the three groups at 1 and 8 weeks after I/R. b Left ventricular ejection fraction (EF). c Left fractional shortening (FS). d Left ventricular internal diastolic dimension (LVIDd). e Left ventricular internal systolic dimension (LVISd). f Relative wall thickness (RWT). g Septal wall thickness (SWT). h Posterior wall thickness (PWT). n = 5–8. *P < 0.05 vs. vehicle. †P < 0.05 vs. low-CU06-1004. #P < 0.05 vs. sham. N.S. not significant. Data are shown as the mean ± SEM.

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