Fig. 6: CU06-1004 reduces cardiac fibrosis and increases capillary density. | Experimental & Molecular Medicine

Fig. 6: CU06-1004 reduces cardiac fibrosis and increases capillary density.

From: CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

Fig. 6

a Representative images of Masson’s trichrome staining at 8 weeks and quantitative summary showing the percentage of fibrosis and viable myocardium. n = 5–6. *P < 0.05 vs. vehicle. †P < 0.05 vs. low CU06-1004. Scale bars: 2000 µm. b Representative images of capillaries stained for CD31 (green) in the infarct zone, border zone, and remote zone at 8 weeks and a summary of their quantification. n = 5. *P < 0.05 vs. vehicle. †P < 0.05 vs. low CU06-1004. Scale bars: 100 µm. N.S. not significant. Data are shown as the mean ± SEM.

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