Table 3 The immunostimulatory functions and mechanism of chlorella.
From: Immunomodulatory functional foods and their molecular mechanisms
Source | Cell type | Function | Model | Reference |
|---|---|---|---|---|
C. vulgaris | White blood cells | Cell number↑ | Animal | |
Peritoneal adherent cells | IL-1α, IL-12, GM-CSF, MIP, TNF- α↑ | Animal | ||
Splenocytes | Cell proliferation↑ IL-2, IL-12, TNF-α, IFN-γ↑ | Animal | ||
IL-12 p40↑ | Animal | |||
Macrophages | Phagocytosis↑ Cell proliferation↑ | Animal | ||
HLA-DA, HLA-DC↑ TNF-α, IL-1β, CD80, CD86↑ | Animal, human | |||
NK cells | Cytotoxicity↑ | Animal, human | ||
T cells | Cell proliferation↑ IFN-γ, IL-2, IL-4↑ | Animal | ||
Blood | IFN-γ, IL-1β, IL-2↑ IgA, IgG, IgM↑ | Animal, human | ||
C. pyrenoidosa | Blood | Antibody production↑ | Human | |
Macrophages | IL-1β, TNF- α↑ | In vitro | ||
Macrophages | Phagocytosis, NO↑ | In vitro | ||
Breast milk | IgA ↑ | Human |
